Kanna / Sceletium tortuosum

By rachelle in 25 May 2022 | 16:31
rachelle

rachelle

 Student
Posts: 17
Member since: 13 Aug 2020
This herbs is becoming increasingly popular in my herbal circles — curious if you've worked with it and/or what your thoughts on it are?
25 May 2022 | 16:31
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David Winston

David Winston

 Instructor
Posts: 858
Member since: 22 Sep 2020
Iknow of it, Herbalgram did an excellent review article on it, 10 (?) years ago. I have not used it as good quality material has been very difficult to source. There are some standardized extracts in the marketplace and I have had some reports of signifiant antidepressant and anxiolytic activity, with little or no adverse effects. Here are a few recent articles on Kanna, both are free full text on PubMed A Chewable Cure "Kanna": Biological and Pharmaceutical Properties of Sceletium tortuosum. Manganyi MC, Bezuidenhout CC, Regnier T, Ateba CN. Molecules. 2021 Apr 28;26(9):2557. doi: 10.3390/molecules26092557. Sceletium for Managing Anxiety, Depression and Cognitive Impairment: A Traditional Herbal Medicine in Modern-Day Regulatory Systems. Brendler T, Brinckmann JA, Feiter U, Gericke N, Lang L, Pozharitskaya ON, Shikov AN, Smith M, Wyk BV. Curr Neuropharmacol. 2021;19(9):1384-1400. doi: 10.2174/1570159X19666210215124737.
26 May 2022 | 20:34
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