Ok. My apologies, I must have misunderstood when you were describing the alkaloidal biochemistry and its similar effects to infer that a tincture might have these qualities. I had been recently using lobelia tincture topically and I suppose in my mind had made this wild extrapolation that I could try a topical tobacco tincture. I had always understood tobacco leaf to have toxicity and knew about its possible support with tobacco addiction. You are right, you did not say that.