Hi again David, I think I've managed to boil my question down to an Aristotelian syllogism. Ha. I'll quickly recount two experiences. 1. I've recently noticed a new(?) pre-migraine symptom: stuffy nose/sinuses. If I treat it like an allergy response, I can stave off migraine. Migraines also tend to occur around my menstrual cycle. 2. When I was on a pharmaceutical anti-anxiety med (Buspirone, which works, albeit mysteriously, on serotonin), a side effect was a terribly stuffy nose, particularly at night. I'm making a logical leap here, but I am feeling that there's a connection between hormones (serotonin, maybe in particular) and this odd stuffy nose phenomenon, and, in turn, migraine. What do you think? Lex

Quick follow up: I'm not asking so much about conditions here as about whether there is ever a connection between serotonin levels and what seems like sinus inflammation.

High serotonin levels can cause a stuffy nose and migraines can cause a stuffy nose, I am not sure if a stuffy nose can cause a migraine or if it is just a early symptom of the migraine.

Thanks! Interesting considering migraine and serotonin levels being related. I'm going to have to do some reading up :)