I personally do not think Calendula is a problem during pregnancy but I know of no studies that prove it is safe, Plantain leaf should be safe but again no studies and alcohol is questionable. In excess it can cause fetal alcohol syndrome, I usually avoid using tinctures during pregnancy, as most women are uncomfortable taking them. I mostly use teas, capsules, vinegar extracts and glycerites and if I use a tincture it is a small dose of something that only works in that form.